ph-8r-lox
Gene name: noneSpecies: coral (plexaura homomalla)
Position of Oxygenation: 8
Substrate: arachidonic acid
Stereospecifity: R
Swissprot Entry:
GenBank Entry: U59223
Sequence: (776 Residues, 76.0 kDa)
MAKLLIILSL FLTWQICAGF LLNDNLCKYK KESNVFSKRS RLCDENQRDC RRFLGWLAPK EEPGDDEYYD CCPGFTKKGR FGCQIKTCIV LPQDVNKFPL MCPFERHADL VLENLFYKLT TPPENPLEYP AETSNILEAV PFPLLNQPSE KVLLRSALKP RLKETEWLIR YIGMSTRNGA LAKKTIENPD IKPFTDYADY AQLLKSFRDE QSKDLISLQI PGVNHTFDLV SMEEYMRYPS QETPFKNIIH NNIWQNDDVF TQQRLAGLNP MSLRKMTNED FNRDFINKTY DWDAAMQRAS GEDSTFSEMI DAGRVYIVEF SYLYDLSNVE DLTERNTTDR REMRGSRAPI CTFVSANVGG VRELKPVAIQ TDQSSDAPVF SPVDGSKWLM AKQEFQRADI TYAEIIEHLL KTHLLMEPIC VIMRRTLSKF HPLHEILKWH CRGLFAVNSV GIKALLNPEE FLHKLFAIGH AGGVELLNKA YPDMSWGVTE FDKNLERRGV DSTDEIPYFP YRDDGLLIWK EVSNFSRDYI NLYYSDDSRV AGDSELGRFF NQLSADGTGT DGGIGMFKGF PAKIETIQDL IDVVKRIVFI PVQHHAINYP VAYYGGFVPN LPTKLYDDPR VPPKEFGFDR LPQYHVAAEQ VALSMSLGSI RYDVLFDYGK HLKDDRAKAI VNKYHERLTG SINDQIAARN QERLQNGKLS YPYLLPKWMP NSIHT
Literature:
- Brash A.R., Boeglin W.E., Chang M.S., Shieh B.H.
"Purification and molecular cloning of an 8R-lipoxygenase from the coral Plexaura homomalla reveal the related primary structures of R- and S-lipoxygenases."
J. Biol. Chem. 271: 20949-20957 (1996)
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