cc-13-lox
Gene name: noneSpecies: cucumber (cucumis sativus)
Position of Oxygenation: 13
Substrate: linoleic acid
Stereospecifity: S
Tissue: lipid bodies
Swissprot Entry: Q42710
GenBank Entry: X92890
Modeled 3D-Structure: file in pdb format (use Rasmol for viewing)
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Sequence: (878 Residues, 99.8 kDa)
MFGIGKNIIE GALNTTGDLA GSVINAGGNI LDRVSSLGGN KIKGKVILMR SNVLDFTEFH SNLLDNFTEL LGGGVSFQLI SATHTSNDSR GKVGNKAYLE RWLTSIPPLF AGESVFQINF QWDENFGFPG AFFIKNGHTS EFFLKSLTLD DVPGYGRVHF DCNSWVYPSG RYKKDRIFFA NHVYLPSQTP NPLRKYREEE LWNLRGDGTG ERKEWDRIYD YDVYNDIADP DVGDHRPILG GTTEYPYPRR GRTGRPRSRR DHNYESRLSP IMSLDIYVPK DENFGHLKMS DFLGYTLKAL SISIKPGLQS IFDVTPNEFD NFKEVDNLFE RGFPIPFNAF KTLTEDLTPP LFKALVRNDG EKFLKFPTPE VVKDNKIGWS TDEEFAREML AGPNPLLIRR LEAFPPTSKL DPNVYGNQNS TITEEHIKHG LDGLTVDEAM KQNRLYIVDF HDALMPYLTR MNATSTKTYA TRTLLLLKDD GTLKPLVIEL ALPHPQGDQL GAISKLYFPA ENGVQKSIWQ LAKAYVTVND VGYHQLISHW LHTHAVLEPF VIATHRQLSV LHPIHKLLVP HYKDTMFINA SARQVLINAN GLIETTHYPS KYSMELSSIL YKDWTFPDQA LPNNLMKRGL AVEDSSAPHG LRLLINDYPF AVDGLDIWSA IKTWVQDYCC LYYKDDNAVQ NDFELQSWWN ELREKGHADK KHEPWWPKMQ TLSELIESCT TIIWIASALH AAVNFGQYPY GGYILNRPTT SRRFMPEVGT AEYKELESNP EKAFLRTICS ELQALVSISI IEILSKHASD EVYLGQRASI DWTSDKIALE AFEKFGKNLF EVENRIMERN KEVNLKNRSG PVNLPYTLLV PSSNEGLTGR GIPNSISI
Literature:
- Hohne M., Nellen A., Schwennesen K., Kindl H.
"Lipid body lipoxygenase characterized by protein fragmentation, cDNA sequence and very early expression of the enzyme during germination of cucumber seeds."
Eur. J. Biochem. 241: 6-11 (1996)
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- Hornung E., Walther M., Kuhn H., Feussner I.
"Conversion of cucumber linoleate 13-lipoxygenase to a 9-lipoxygenating species by site-directed mutagenesis."
Proc. Natl. Acad. Sci. U.S.A. 96: 4192-4197 (1999)
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