Deutsches Krebsforschungszentrum 
German Cancer Resarch CenterLOX-DB - LipOXygenases DataBase
Lipoxygenases...
What are Lipoxygenases?
Lipoxygenases and
cancer research
Database...
Search
Display all entries
Alignments
Sequence Comparison
Blast Search
Search Literature
Search Literature (adv.)
Misc...
Image Gallery
Links
Forum
Contact
Guestbook
Home

st-9-lox

Gene name: none

Species: potato (solanum tuberosum)

Position of Oxygenation: 9

Substrate: linoleic acid

Stereospecifity: S

Swissprot Entry: O49150

GenBank Entry: AF039651

Modeled 3D-Structure: file in pdb-format (use Rasmol for viewing)

 - View with Webmol by Dirk Walther


left-click on the structure to rotate.
right-click on the structure to change properties.


Sequence: (864 Residues, 97.3 kDa)

MNIGQIMGGR ELFGGHDDSK KVKGTVVMMK KNALDFTDLA GSLTDIAFDV LGQKVSFQLI SSVQGDPTNG LQGKHSNPAY LENSLFTLTP LTAGSETAFG VTFDWNEEFG VPGAFIIKNT HINEFFLKSL TLEDVPNHGK VHFDCNSWVY PSFRYKSDRI FFANQPYLPS KTPELLRKYR ENELLTLRGD GTGKREAWDR IYDYDIYNDL GNPDQGKENV RTTLGGSAEY PYPRRGRTGR PPTRTDPKSE SRIPLLLSLD IYVPRDERFG HLKMSDFLTY ALKSIVQFIL PELHALFDGT PNEFDSFEDV LRLYEGGIKL PQGPLFKALT AAIPLEMIKE LLRTDGEGIL RFPTPLVIKD SKTAWRTDEE FAREMLAGVN PIIISRLQEF PPKSKLDPEA YGNQNSTITA EHIEDKLDGL TVDEAMNNNK LFILNHHDLL IPYLRRINTT ITKSYASRTL LFLQDNGSLK PLAIELSLPH PDGDQFGVTS KVYTPSDQGV ESSIWQLAKA YVAVNDAGVH QLISHWLNTH AVIEPFVIAT NRQLSVLHPI HKLLYPHFRD TMNINASARQ ILINAGGVLE STVFQSKFAL EMSAVVYKDW VFPDQALPAD LVKRGVAVED SSSPHGVRLL IEDYPYAVDG LEIWSAIKSW VTDYCSFYYG SDEEILKDNE LQAWWKELRE VGHGDKKNEP WWPEMETPQE LIDSCTTIIW IASALHAAVN FGQYPYAGYL PNRPTVSRRF MPEPGTPEYE ELKKNPDKAF LKTITAQLQT LLGVSLVEIL SRHTTDEIYL GQRESPEWTK DKEPLAAFDK FGKKLTDIEK QIIQRNGDNI LTNRSGPVNA PYTLLFPTSE GGLTGKGIPN SVSI


Literature:

  • Chen X., Reddanna P., Reddy G.R., Kidd R., Hildenbrandt G., Reddy C.C.
    "Expression, purification, and characterization of a recombinant 5-lipoxygenase from potato tuber."
    Biochem. Biophys. Res. Commun. 243: 438-443 (1998)
    more...

  • Butovich I.A., Reddy C.C.
    "Inhibition of lipoxygenase from S. Tuberosum (L.) by linoleyl hydroxamic acid: kinetic and EPR spectral evidence for a two-step reaction."
    Biochem. J. 365: 865-871 (2002)
    more...