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hv-lox-a

Gene name: LOX1.1 or LOXA

Species: barley (hordeum vulgare)

Position of Oxygenation: 9

Substrate: linoleic acid

Stereospecifity: S

Swissprot Entry: P29114

GenBank Entry: L35931

Modeled 3D-Structure: file in pdb-format (use Rasmol for viewing)

 - View with Webmol by Dirk Walther


left-click on the structure to rotate.
right-click on the structure to change properties.


Sequence: (862 Residues, 96.4 kDa)

MLLGGLIDTL TGANKSARLK GTVVLMRKNV LDLNDFGATI IDGIGEFLGK GVTCQLISST AVDQDNGGRG KVGAEAELEQ WVTSLPSLTT GESKFGLTFD WEVEKLGVPG AIVVNNYHSS EFLLKTITLH DVPGRSGNLT FVANSWIYPA ANYRYSRVFF ANDTYLPSQM PAALKPYRDD ELRNLRGDDQ QGPYQEHDRI YRYDVYNDLG EGRPILGGNS DHPYPRRGRT ERKPNASDPS LESRLSLLEQ IYVPRDEKFG HLKTSDFLGY SIKAITQGIL PAVRTYVDTT PGEFDSFQDI INLYEGGIKL PKVAALEELR KQFPLQLIKD LLPVGGDSLL KLPVPHIIQE NKQAWRTDEE FAREVLAGVN PVMITRLTEF PPKSSLDPSK FGDHTSTITA EHIEKNLEGL TVQQALESNR LYILDHHDRF MPFLIDVNNL PGNFIYATRT LFFLRGDGRL TPLAIELSEP IIQGGLTTAK SKVYTPVPSG SVEGWVWELA KAYVAVNDSG WHQLVSHWLN THAVMEPFVI STNRHLSVTH PVHKLLSPHY RDTMTINALA RQTLINAGGI FEMTVFPGKF ALGMSAVVYK DWKFTEQGLP DDLIKRGMAV EDPSSPYKVR LLVSDYPYAA DGLAIWHAIE QYVSEYLAIY YPNDGVLQGD TEVQAWWKET REVGHGDLKD APWWPKMQSV PELAKACTTI IWIGSALHAA VNFGQYPYAG FLPNRPTVSR RRMPEPGTEE YAELERDPER AFIHTITSQI QTIIGVSLLE VLSKHSSDEL YLGQRDTPEW TSDPKALEVF KRFSDRLVEI ESKVVGMNHD PELKNRNGPA KFPYMLLYPN TSDHKGAAAG LTAKGIPNSI SI


Literature:

  • van Mechelen J.R., Smits M., Douma A.C., Rouster J., Cameron-Mills V., Heidekamp F., Valk B.E.
    "Primary structure of a lipoxygenase from barley grain as deduced from its cDNA sequence."
    Biochim. Biophys. Acta 1254: 221-225 (1995)
    more...

  • Doderer A., Kokkelink I., van der Veen S., Valk B.E., Schram A.W., Douma A.C.
    "Purification and characterization of two lipoxygenase isoenzymes from germinating barley."
    Biochim. Biophys. Acta 1120: 97-104 (1992)
    more...

  • Holtman W.L., Roberts M.R., Oppedijk B.J., Testerink C., van Zeijl M.J., Wang M.
    "14-3-3 proteins interact with a 13-lipoxygenase, but not with a 9-lipoxygenase."
    FEBS Lett. 474: 48-52 (2000)
    more...