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gm-lox-3

Gene name: LOX1.3 or LOX3

Species: soybean (glycine max)

Position of Oxygenation: 13 / 9

Substrate: linoleic acid

Stereospecifity: S

Swissprot Entry: P09186

GenBank Entry: U50081

PDB Entry: 1IK3

IMB Jena: 1IK3

Structure: file in pdb format (use Rasmol for viewing)

View Structure with Webmol by Dirk Walther


left-click on the structure to rotate.
right-click on the structure to change properties.


Sequence: (857 Residues, 96.8 kDa)

MLGGLLHRGH KIKGTVVLMR KNVLHVNSVT SVGGIIGQGL DLVGSTLDTL TAFLGRPVSL QLISATKADA NGKGKLGKAT FLEGIITSLP TLGAGQSAFK INFEWDDGSG ILGAFYIKNF MQTEFFLVSL TLEDIPNHGS IHFVCNSWIY NAKLFKSDRI FFANQTYLPS ETPAPLVKYR EEELHNLRGD GTGERKEWER VYDYDVYNDL GDPDKGENHA RPVLGGNDTF PYPRRGRTGR KPTRKDPNSE SRSNDVYLPR DEAFGHLKSS DFLTYGLKSV SQNVLPLLQS AFDLNFTPRE FDSFDEVHGL YSGGIKLPTD IISKISPLPV LKEIFRTDGE QALKFPPPKV IQVSKSAWMT DEEFAREMLA GVNPNLIRCL KEFPPRSKLD SQVYGDHTSQ ITKEHLEPNL EGLTVDEAIQ NKRLFLLGHH DPIMPYLRRI NATSTKAYAT RTILFLKNDG TLRPLAIELS LPHPQGDQSG AFSQVFLPAD EGVESSIWLL AKAYVVVNDS CYHQLVSHWL NTHAVVEPFI IATNRHLSVV HPIYKLLHPH YRDTMNINGL ARLSLVNDGG VIEQTFLWGR YSVEMSAVVY KDWVFTDQAL PADLIKRGMA IEDPSCPHGI RLVIEDYPYA VDGLEIWDAI KTWVHEYVFL YYKSDDTLRE DPELQACWKE LVEVGHGDKK NEPWWPKMQT REELVEACAI IIWTASALHA AVNFGQYPYG GLILNRPTLS RRFMPEKGSA EYEELRKNPQ KAYLKTITPK FQTLIDLSVI EILSRHASDE VYLGERDNPN WTSDTRALEA FKRFGNKLAQ IENKLSERNN DEKLRNRCGP VQMPYTLLLP SSKEGLTFRG IPNSISI


Literature:

  • Skrzypczak-Jankun E., Amzel L.M., Kroa B.A., Funk M.O. Jr.
    "Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme."
    Proteins 29: 15-31 (1997)
    more...

  • Skrzypczak-Jankun E., Bross R.A., Carroll R.T., Dunham W.R., Funk M.O. Jr.
    "Three-dimensional structure of a purple lipoxygenase."
    J. Am. Chem. Soc. 123:10814-10820 123: 10814-10820 (2001)
    more...

  • Yenofsky R.L., Fine M., Liu C.
    "Isolation and characterization of a soybean (Glycine max) lipoxygenase-3 gene."
    Mol. Gen. Genet. 211: 215-222 (1988)

  • Pham C., Jankun J., Skrzypczak-Jankun E., Flowers R.A., Funk M.O. Jr.
    "Structural and thermochemical characterization of lipoxygenase-catechol complexes."
    Biochemistry 37: 17952-17957 (1998)
    more...