Deutsches Krebsforschungszentrum 
German Cancer Resarch CenterLOX-DB - LipOXygenases DataBase
What are Lipoxygenases?
Lipoxygenases and
cancer research
Display all entries
Sequence Comparison
Blast Search
Search Literature
Search Literature (adv.)
Image Gallery

LOX-DB - Literature related to ss-12-lox

Found 25 entries:

  • Natarajan R., Gerrity R.G., Gu J.L., Lanting L., Thomas L., Nadler J.L.
    "Role of 12-lipoxygenase and oxidant stress in hyperglycaemia-induced acceleration of atherosclerosis in a diabetic pig model."
    Diabetologia 45: 125-133 (2002)

  • Schewe T
    "15-lipoxygenase-1: a prooxidant enzyme."
    Biol Chem 383: 365-374 (2002)

  • Muller K, Altmann R, Prinz H
    "2-Arylalkyl-substituted anthracenones as inhibitors of 12-lipoxygenase enzymes. 2. Structure-activity relationships of the linker chain."
    Eur J Med Chem 37: 83-89 (2002)

  • Schewe T., Sadik C., Klotz L.O., Yoshimoto T., Kuhn H., Sies H.
    "Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase."
    Biol. Chem. 382: 1687-1696 (2001)

  • Patricia MK, Natarajan R, Dooley AN, Hernandez F, Gu JL, Berliner JA, Rossi JJ, Nadler JL, Meidell RS, Hedrick CC
    "Adenoviral delivery of a leukocyte-type 12 lipoxygenase ribozyme inhibits effects of glucose and platelet-derived growth factor in vascular endothelial and smooth muscle cells."
    Circ Res 88: 659-665 (2001)

  • Moody JS, Kozak KR, Ji C, Marnett LJ
    "Selective oxygenation of the endocannabinoid 2-arachidonylglycerol by leukocyte-type 12-lipoxygenase."
    Biochemistry 40: 861-866 (2001)

  • Muller K, Altmann R, Prinz H
    "2-arylalkyl-substituted anthracenones as inhibitors of 12-lipoxygenase enzymes. 1. Structure-activity relationships of the terminal aryl ring."
    Eur J Med Chem 36: 569-575 (2001)

  • Tornhamre S., Elmqvist A., Lindgren J.A.
    "15-Lipoxygenation of leukotriene A(4). Studies Of 12- and 15-lipoxygenase efficiency to catalyze lipoxin formation."
    Biochim. Biophys. Acta 1484: 298-306 (2000)

  • Iwase H, Sakurada K, Hatanaka K, Kobayashi M, Takatori T
    "Effect of cytochrome c on the linoleic acid-degrading activity of porcine leukocyte 12-lipoxygenase."
    Free Radic Biol Med 28: 912-919 (2000)

  • Juranek I , Suzuki H , Yamamoto S
    "Affinities of various mammalian arachidonate lipoxygenases and cyclooxygenases for molecular oxygen as substrate."
    Biochim Biophys Acta 1436: 509-518 (1999)

  • Richards KM, Moody JS, Marnett LJ
    "Mechanism of inhibition of porcine leukocyte 12-lipoxygenase by the isoform-specific inhibitor 4-(2-oxapentadeca-4-yne)phenylpropanoic acid."
    Biochemistry 38: 16529-16538 (1999)

  • Schwarz K, Borngraber S, Anton M, Kuhn H
    "Probing the substrate alignment at the active site of 15-lipoxygenases by targeted substrate modification and site-directed mutagenesis. Evidence for an inverse substrate orientation."
    Biochemistry 37: 15327-15335 (1998)

  • Natarajan R, Rosdahl J, Gonzales N, Bai W
    "Regulation of 12-lipoxygenase by cytokines in vascular smooth muscle cells."
    Hypertension 30: 873-879 (1997)

  • Borngraber S., Kuban R.J., Anton M., Kuhn H.
    "Phenylalanine 353 is a primary determinant for the positional specificity of mammalian 15-lipoxygenases."
    J. Mol. Biol. 264: 1145-1153 (1996)

  • Gorins G., Kuhnert L., Johnson C.R., Marnett L.J.
    "(Carboxyalkyl)benzyl propargyl ethers as selective inhibitors of leukocyte-type 12-lipoxygenases."
    J. Med. Chem. 39: 4871-4878 (1996)

  • Natarajan R , Bai W , Rangarajan V , Gonzales N , Gu JL , Lanting L , Nadler JL
    "Platelet-derived growth factor BB mediated regulation of 12-lipoxygenase in porcine aortic smooth muscle cells."
    J Cell Physiol 169: 391-400 (1996)

  • Kishimoto K, Nakamura M, Suzuki H, Yoshimoto T, Yamamoto S, Takao T, Shimonishi Y, Tanabe T
    "Suicide inactivation of porcine leukocyte 12-lipoxygenase associated with its incorporation of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid derivative."
    Biochim Biophys Acta 1300: 56-62 (1996)

  • Ikawa H, Yamamoto K, Takahashi Y, Ueda N, Hayashi Y, Yamamoto S, Ishimura K, Irahara M, Aono T
    "Arachidonate 12-lipoxygenase in porcine anterior pituitary cells: its localization and possible function in gonadotrophs."
    J Endocrinol 148: 33-41 (1996)

  • Ueda N, Yamamoto K., Yamamoto S., Tokunaga T., Shirakawa E., Shinkai H., Ogawa M., Sato T., Kudo I., Inoue K., et al.
    "Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist."
    Biochim. Biophys. Acta 1254: 127-134 (1995)

  • Coscelli MB , Davoli R , Russo V
    "A TaqI polymorphism at the porcine arachidonate 12-lipoxygenase (ALOX12) locus."
    Anim Genet 26: 446-447 (1995)

  • Suzuki H., Kishimoto K., Yoshimoto T., Yamamoto S., Kanai F., Ebina Y., Miyatake A., Tanabe T.
    "Site-directed mutagenesis studies on the iron-binding domain and the determinant for the substrate oxygenation site of porcine leukocyte arachidonate 12-lipoxygenase."
    Biochim. Biophys. Acta 1210: 308-316 (1994)

  • Kuhn H., Belkner J., Suzuki H., Yamamoto S.
    "Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities."
    J. Lipid Res. 35: 1749-1759 (1994)

  • Reddy RG, Yoshimoto T, Yamamoto S, Marnett LJ
    "Expression, purification, and characterization of porcine leukocyte 12-lipoxygenase produced in the methylotrophic yeast, Pichia pastoris."
    Biochem Biophys Res Commun 205: 381-388 (1994)

  • Arakawa T, Oshima T, Kishimoto K, Yoshimoto T, Yamamoto S
    "Molecular structure and function of the porcine arachidonate 12-lipoxygenase gene."
    J Biol Chem 267: 12188-12191 (1992)

  • Yoshimoto T., Suzuki H., Yamamoto S., Takai T., Yokoyama C., Tanabe T.
    "Cloning and sequence analysis of the cDNA for arachidonate 12-lipoxygenase of porcine leukocytes."
    Proc. Natl. Acad. Sci. U.S.A. 87: 2142-2146 (1990)