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German Cancer Resarch CenterLOX-DB - LipOXygenases DataBase
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LOX-DB - Literature related to rn-12-lox

Found 25 entries:

  • Wang H, Li J, Follett PL, Zhang Y, Cotanche DA, Jensen FE, Volpe JJ, Rosenberg PA
    "12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes."
    Eur J Neurosci 20: 2049-58 (2004)

  • Schewe T
    "15-lipoxygenase-1: a prooxidant enzyme."
    Biol Chem 383: 365-374 (2002)

  • Reddy MA , Adler SG , Kim YS , Lanting L , Rossi J , Kang SW , Nadler JL , Shahed A , Natarajan R
    "Interaction of MAPK and 12-lipoxygenase pathways in growth and matrix protein expression in mesangial cells."
    Am J Physiol Renal Physiol 283: F985-94 (2002)

  • Nogata Y, Sekiya K, Ohta H, Kusumoto K, Ishizu T
    "Inhibitors of platelet lipoxygenase from Ponkan fruit."
    Phytochemistry 56: 729-732 (2001)

  • Gonzalez-Nunez D, Claria J, Rivera F, Poch E
    "Increased levels of 12(S)-HETE in patients with essential hypertension."
    Hypertension 37: 334-338 (2001)

  • Wen Y, Gu J, Liu Y, Wang PH, Sun Y, Nadler JL
    "Overexpression of 12-lipoxygenase causes cardiac fibroblast cell growth."
    Circ Res 88: 70-76 (2001)

  • Kawajiri H, Zhuang D, Qiao N, Yoshimoto T, Yamamoto M, Iseki S, Hamaguchi K
    "Expression of arachidonate 12-lipoxygenase in rat tissues: a possible role in glucagon secretion."
    J Histochem Cytochem 48: 1411-1419 (2000)

  • DelliPizzi A, Guan H, Tong X, Takizawa H, Nasjletti A
    "Lipoxygenase-dependent mechanisms in hypertension."
    Clin Exp Hypertens 22: 181-192 (2000)

  • Chen W., Glasgow W., Murphy E., Steenbergen C.
    "Lipoxygenase metabolism of arachidonic acid in ischemic preconditioning and PKC-induced protection in heart."
    Am. J. Physiol. 276: H2094-2101 (1999)

  • Wang MM, Reynaud D, Pace-Asciak CR
    "In vivo stimulation of 12(S)-lipoxygenase in the rat skin by bradykinin and platelet activating factor: formation of 12(S)-HETE and hepoxilins, and actions on vascular permeability."
    Biochim Biophys Acta 1436: 354-362 (1999)

  • Kamitani H, Ikawa H, Hsi LC, Watanabe T, DuBois RN, Eling TE
    "Regulation of 12-lipoxygenase in rat intestinal epithelial cells during differentiation and apoptosis induced by sodium butyrate."
    Arch Biochem Biophys 368: 45-55 (1999)

  • Zhang H , Akbar M , Kim HY
    "Melatonin: an endogenous negative modulator of 12-lipoxygenation in the rat pineal gland."
    Biochem J 344: 487-493 (1999)

  • Takizawa H., DelliPizzi A.M., Nasjletti A.
    "Prostaglandin I2 contributes to the vasodepressor effect of baicalein in hypertensive rats."
    Hypertension 31: 866-871 (1998)

  • Tang DG, Honn KV
    "Apoptosis of W256 carcinosarcoma cells of the monocytoid origin induced by NDGA involves lipid peroxidation and depletion of GSH: role of 12-lipoxygenase in regulating tumor cell survival."
    J Cell Physiol 172: 155-170 (1997)

  • Kawajiri H, Qiao N, Zhuang DM, Yoshimoto T, Hagiya H, Yamamoto S, Sei H, Morita Y
    "Diurnal change of arachidonate 12-lipoxygenase in rat pineal gland."
    Biochem Biophys Res Commun 238: 229-233 (1997)

  • Stern N, Kisch ES, Knoll E
    "Platelet lipoxygenase in spontaneously hypertensive rats."
    Hypertension 27: 1149-1152 (1996)

  • Stern N, Nozawa K, Kisch E, Tuck ML, Golub M, Eggena P, Knoll E
    "Tonic inhibition of renin secretion by the 12 lipoxygenase pathway: augmentation by high salt intake."
    Endocrinology 137: 1878-1884 (1996)

  • Ma Z , Ramanadham S , Corbett JA , Bohrer A , Gross RW , McDaniel ML , Turk J
    "Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism."
    J Biol Chem 271: 1029-1042 (1996)

  • Normandin M, Gagne J, Bernard J, Elie R, Miceli D, Baudry M, Massicotte G
    "Involvement of the 12-lipoxygenase pathway of arachidonic acid metabolism in homosynaptic long-term depression of the rat hippocampus."
    Brain Res 730: 40-46 (1996)

  • Bleich D, Chen S, Gu JL, Thomas L, Scott S, Gonzales N, Natarajan R, Nadler JL
    "Interleukin-1 beta regulates the expression of a leukocyte type of 12-lipoxygenase in rat islets and RIN m5F cells."
    Endocrinology 136: 5736-5744 (1995)

  • Herbertsson H, Hammarstrom S
    "Subcellular localization of 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid binding sites in Lewis lung carcinoma cells."
    Biochim Biophys Acta 1244: 191-197 (1995)

  • Hada T., Hagiya H., Suzuki H., Arakawa T., Nakamura M., Matsuda S., Yoshimoto T., Yamamoto S., Azekawa T., Morita Y., Ishimura K., Kim H.Y.
    "Arachidonate 12-lipoxygenase of rat pineal glands: catalytic properties and primary structure deduced from its cDNA."
    Biochim. Biophys. Acta 1211: 221-228 (1994)

  • Chen YQ, Duniec ZM, Liu B, Hagmann W, Gao X, Shimoji K, Marnett LJ, Johnson CR, Honn KV
    "Endogenous 12(S)-HETE production by tumor cells and its role in metastasis."
    Cancer Res 54: 1574-1579 (1994)

  • Watanabe T., Medina J.F., Haeggstroem J.Z., Raadmark O.P., Samuelsson B.
    "Molecular cloning of a 12-lipoxygenase cDNA from rat brain."
    Eur. J. Biochem. 212: 605-612 (1993)

  • Watanabe T., Haeggstrom J.Z.
    "Rat 12-lipoxygenase: mutations of amino acids implicated in the positional specificity of 15- and 12-lipoxygenases."
    Biochem. Biophys. Res. Commun. 192: 1023-1029 (1993)