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LOX-DB - Literature related to h-5-lox


Found 107 entries:

  • Bindu PH , Sastry GM , Sastry GN
    "Characterization of calcium and magnesium binding domains of human 5-lipoxygenase."
    Biochem Biophys Res Commun 320: 461-467 (2004)
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  • Pande AH, Moe D, Nemec KN, Qin S, Tan S, Tatulian SA
    "Modulation of human 5-lipoxygenase activity by membrane lipids."
    Biochemistry 43: 14653-14666 (2004)
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  • Luo M, Pang CW, Gerken AE, Brock TG
    "Multiple nuclear localization sequences allow modulation of 5-lipoxygenase nuclear import."
    Traffic 5: 847-854 (2004)
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  • Chen X , Wang S , Wu N , Sood S , Wang P , Jin Z , Beer DG , Giordano TJ , Lin Y , Shih WC , Lubet RA , Yang CS
    "Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis."
    Clin Cancer Res 10: 6703-9 (2004)
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  • Ramires R, Caiaffa MF, Tursi A, Haeggstrom JZ, Macchia L
    "Novel inhibitory effect on 5-lipoxygenase activity by the anti-asthma drug montelukast."
    Biochem Biophys Res Commun 324: 815-21 (2004)
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  • Goodman JE, Bowman ED, Chanock SJ, Alberg AJ, Harris CC
    "Arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) polymorphisms and colon cancer risk."
    Carcinogenesis 25: 2467-2472 (2004)
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  • Moretti RM, Montagnani Marelli M, Sala A, Motta M, Limonta P
    "Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase."
    Int J Cancer 112: 87-93 (2004)
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  • Martel-Pelletier J , Mineau F , Fahmi H , Laufer S , Reboul P , Boileau C , Lavigne M , Pelletier JP
    "Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids."
    Arthritis Rheum 50: 3925-3933 (2004)
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  • Manev R , Manev H
    "5-Lipoxygenase as a putative link between cardiovascular and psychiatric disorders."
    Crit Rev Neurobiol 16: 181-6 (2004)
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  • Maccarrone M , Taccone-Gallucci M , Finazzi-Agro A
    "5-Lipoxygenase-mediated mitochondrial damage and apoptosis of mononuclear cells in ESRD patients."
    Kidney Int Suppl 84: 33-36 (2003)
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  • Jiang WG, Douglas-Jones A, Mansel RE
    "Levels of expression of lipoxygenases and cyclooxygenase-2 in human breast cancer."
    Prostaglandins Leukot Essent Fatty Acids 69: 275-281 (2003)
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  • Zhi H , Zhang J , Hu G , Lu J , Wang X , Zhou C , Wu M , Liu Z
    "The deregulation of arachidonic acid metabolism-related genes in human esophageal squamous cell carcinoma."
    Int J Cancer 106: 327-333 (2003)
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  • Mehrabian M , Allayee H
    "5-lipoxygenase and atherosclerosis."
    Curr Opin Lipidol 14: 447-457 (2003)
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  • Kozak K.R., Gupta R.A., Moody J.S., Ji C., Boeglin W.E., DuBois R.N., Brash A.R., Marnett L.J.
    "15-lipoxygenase metabolism of 2-arachidonylglycerol: Generation of a PPARalpha agonist."
    J. Biol. Chem. 277: 23278-23286 (2002)
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  • Burkert E., Radmark O., Samuelsson B., Steinhilber D., Werz O.
    "Hypertonicity suppresses ionophore-induced product formation and translocation of 5-lipoxygenase in human leukocytes."
    J. Leukoc. Biol. 71: 477-486 (2002)
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  • Hemak J, Gale D, Brock TG
    "Structural characterization of the catalytic domain of the human 5-lipoxygenase enzyme."
    J Mol Model (Online) 8: 102-112 (2002)
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  • Kulkarni S, Das S, Funk CD, Murray D, Cho W
    "Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase."
    J Biol Chem 277: 13167-13174 (2002)
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  • Maccarrone M , Manca-di-Villahermosa S , Meloni C , Massoud R , Mascali A , Guarina R , Finazzi-Agro A , Taccone-Gallucci M
    "Arachidonate cascade, apoptosis, and vitamin E in peripheral blood mononuclear cells from hemodialysis patients."
    Am J Kidney Dis 40: 600-610 (2002)
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  • Werz O, Burkert E, Fischer L, Szellas D, Dishart D, Samuelsson B, Radmark O, Steinhilber D
    "Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes."
    FASEB J 16: 1441-1443 (2002)
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  • Tong WG, Ding XZ, Adrian TE
    "The mechanisms of lipoxygenase inhibitor-induced apoptosis in human breast cancer cells."
    Biochem Biophys Res Commun 296: 942-948 (2002)
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  • Taylor PM, Woodfield RJ, Hodgkin MN, Pettitt TR, Martin A, Kerr DJ, Wakelam MJ
    "Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway."
    Oncogene 21: 5765-5772 (2002)
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  • Zeng ZZ , Yellaturu CR , Neeli I , Rao GN
    "5(S)-Hydroxyeicosatetraenoic Acid Stimulates DNA Synthesis in Human Microvascular Endothelial Cells via Activation of Jak/STAT and Phosphatidylinositol 3-Kinase/Akt Signaling, Leading to Induction of Expression of Basic Fibroblast Growth Factor 2."
    J Biol Chem 277: 41213-41219 (2002)
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  • Hennig R, Ding XZ, Tong WG, Schneider MB, Standop J, Friess H, Buchler MW, Pour PM, Adrian TE
    "5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue."
    Am J Pathol 161: 421-428 (2002)
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  • Hendel J, Ahnfelt-Ronne I, Nielsen OH
    "Expression of 5-lipoxygenase mRNA is unchanged in the colon of patients with active inflammatory bowel disease."
    Inflamm Res 51: 423-426 (2002)
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  • Flamand N, Surette ME, Picard S, Bourgoin S, Borgeat P
    "Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils."
    Mol Pharmacol 62: 250-256 (2002)
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  • Burkert E , Radmark O , Steinhilber D , Werz O
    "Monocyte-derived soluble protein confers 5-lipoxygenase activity Ca2+-dependent."
    Biochem Biophys Res Commun 295: 985-991 (2002)
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  • Schewe T, Kuhn H, Sies H
    "Flavonoids of cocoa inhibit recombinant human 5-lipoxygenase."
    J Nutr 132: 1825-1829 (2002)
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  • Haeggstrom JZ , Wetterholm A
    "Enzymes and receptors in the leukotriene cascade."
    Cell Mol Life Sci 59: 742-753 (2002)
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  • Uhl J, Klan N, Rose M, Entian KD, Werz O, Steinhilber D
    "The 5-lipoxygenase promoter is regulated by DNA methylation."
    J Biol Chem 277: 4374-4379 (2002)
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  • Hanaka H, Shimizu T, Izumi T
    "Nuclear-localization-signal-dependent and nuclear-export-signal-dependent mechanisms determine the localization of 5-lipoxygenase."
    Biochem J 361: 505-514 (2002)
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  • Werz O, Burkert E, Samuelsson B, Radmark O, Steinhilber D
    "Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes."
    Blood 99: 1044-1052 (2002)
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  • Shureiqi I., Lippman S.M.
    "Lipoxygenase Modulation to Reverse Carcinogenesis"
    Cancer Res. 61: 6307-6312 (2001)
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  • Walther M., Ivanov I., Myagkova G., Kuhn H.
    "Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis."
    Chem. Biol. 8: 779-790 (2001)
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  • Chen X.S., Funk C.D.
    "The N-terminal 'beta-barrel' domain of 5-lipoxygenase is essential for nuclear membrane translocation."
    J. Biol. Chem. 276: 811-818 (2001)
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  • Schwarz K., Walther M., Anton M., Gerth C., Feussner I., Kuhn H.
    "Structural basis for lipoxygenase specificity. Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis."
    J. Biol. Chem. 276: 773-779 (2001)
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  • Schwarz K., Gerth C., Anton M., Kuhn H.
    "Alterations in leukotriene synthase activity of the human 5-lipoxygenase by site-directed mutagenesis affecting its positional specificity."
    Biochemistry 39: 14515-14521 (2000)
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  • Hammarberg T., Provost P., Persson B., Radmark O.
    "The N-terminal domain of 5-lipoxygenase binds calcium and mediates calcium stimulation of enzyme activity."
    J. Biol. Chem. 275: 38787-38793 (2000)
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  • Coffey MJ, Phare SM, Peters-Golden M
    "Prolonged exposure to lipopolysaccharide inhibits macrophage 5-lipoxygenase metabolism via induction of nitric oxide synthesis."
    J Immunol 165: 3592-3598 (2000)
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  • Manev H, Uz T, Sugaya K, Qu T
    "Putative role of neuronal 5-lipoxygenase in an aging brain."
    FASEB J 14: 1464-1469 (2000)
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  • Zhang YY, Hammarberg T, Radmark O, Samuelsson B, Ng CF, Funk CD, Loscalzo J
    "Analysis of a nucleotide-binding site of 5-lipoxygenase by affinity labelling: binding characteristics and amino acid sequences."
    Biochem J 351: 697-707 (2000)
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  • Reddy KV, Hammarberg T, Radmark O
    "Mg2+ activates 5-lipoxygenase in vitro: dependency on concentrations of phosphatidylcholine and arachidonic acid."
    Biochemistry 39: 1840-1848 (2000)
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  • Silverman ES, Drazen JM
    "Genetic variations in the 5-lipoxygenase core promoter. Description and functional implications."
    Am J Respir Crit Care Med 161: S77-80 (2000)
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  • Wachtershauser A, Steinhilber D, Loitsch SM, Stein J
    "Expression of 5-lipoxygenase by human colorectal carcinoma Caco-2 cells during butyrate-induced cell differentiation."
    Biochem Biophys Res Commun 268: 778-783 (2000)
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  • Werz O, Klemm J, Samuelsson B, Radmark O
    "5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases."
    Proc Natl Acad Sci U S A 97: 5261-5266 (2000)
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  • Brown NL, Slater DM, Alvi SA, Elder MG, Sullivan MH, Bennett PR
    "Expression of 5-lipoxygenase and 5-lipoxygenase-activating protein in human fetal membranes throughout pregnancy and at term."
    Mol Hum Reprod 5: 668-674 (1999)
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  • Datta K, Biswal SS, Kehrer JP
    "The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP."
    Biochem J 340: 371-375 (1999)
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  • Hong SH, Avis I, Vos MD, Martinez A, Treston AM, Mulshine JL
    "Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors."
    Cancer Res 59: 2223-2228 (1999)
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  • Bonizzi G, Piette J, Schoonbroodt S, Greimers R, Havard L, Merville MP, Bours V
    "Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity."
    Mol Cell Biol 19: 1950-1960 (1999)
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  • Uz T, Dwivedi Y, Savani PD, Impagnatiello F, Pandey G, Manev H
    "Glucocorticoids stimulate inflammatory 5-lipoxygenase gene expression and protein translocation in the brain."
    J Neurochem 73: 693-699 (1999)
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  • Provost P, Samuelsson B, Radmark O
    "Interaction of 5-lipoxygenase with cellular proteins."
    Proc Natl Acad Sci U S A 96: 1881-1885 (1999)
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  • Drazen JM , Yandava CN , Dube L , Szczerback N , Hippensteel R , Pillari A , Israel E , Schork N , Silverman ES , Katz DA , Drajesk J
    "Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment."
    Nat Genet 22: 168-170 (1999)
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  • Phare SM , Peters-Golden M , Coffey MJ
    "Alveolar lining fluid regulates mononuclear phagocyte 5-lipoxygenase metabolism."
    Eur Respir J 12: 1141-1146 (1998)
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  • Chen XS, Zhang YY, Funk CD
    "Determinants of 5-lipoxygenase nuclear localization using green fluorescent protein/5-lipoxygenase fusion proteins."
    J Biol Chem 273: 31237-31244 (1998)
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  • Ghosh J, Myers CE
    "Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells."
    Proc Natl Acad Sci U S A 95: 13182-13187 (1998)
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  • Lepley RA, Fitzpatrick FA
    "5-Lipoxygenase compartmentalization in granulocytic cells is modulated by an internal bipartite nuclear localizing sequence and nuclear factor kappa B complex formation."
    Arch Biochem Biophys 356: 71-76 (1998)
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  • Silverman ES, Du J, De Sanctis GT, Radmark O, Samuelsson B, Drazen JM, Collins T
    "Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants."
    Am J Respir Cell Mol Biol 19: 316-323 (1998)
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  • Spanbroek R , Stark HJ , Janssen-Timmen U , Kraft S , Hildner M , Andl T , Bosch FX , Fusenig NE , Bieber T , Radmark O , Samuelsson B , Habenicht AJ
    "5-Lipoxygenase expression in Langerhans cells of normal human epidermis."
    Proc Natl Acad Sci U S A 95: 663-668 (1998)
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  • Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB
    "Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models."
    Inflamm Res 46: 168-179 (1997)
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  • In KH, Asano K, Beier D, Grobholz J, Finn PW, Silverman EK, Silverman ES, Collins T, Fischer AR, Keith TP, Serino K, Kim SW, De Sanctis GT, Yandava C, Pillari A, Rubin P, Kemp J, Israel E, Busse W, Le
    "Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription."
    J Clin Invest 99: 1130-1137 (1997)
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  • Chen CJ, Huang HS, Lee YT, Yang CY, Chang WC
    "Characterization and purification of a lipoxygenase inhibitor in human epidermoid carcinoma A431 cells."
    Biochem J 327: 193-198 (1997)
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  • Iversen L, Kragballe K, Ziboh VA
    "Significance of leukotriene-A4 hydrolase in the pathogenesis of psoriasis."
    Skin Pharmacol 10: 169-177 (1997)
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  • Ponton A, Thirion JP, Sirois P
    "Repression of the 5-lipoxygenase gene by c-myb overexpression in differentiated HL-60 cells."
    Prostaglandins 53: 49-58 (1997)
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  • Bhatia PA, Brooks CD, Basha A, Ratajczyk JD, Gunn BP, Bouska JB, Lanni C, Young PR, Bell RL, Carter GW
    "5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones."
    J Med Chem 39: 3938-3950 (1996)
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  • Kaminski WE, Jendraschak E, Baumann K, Kiefl R, Fischer S, Marcus AJ, Broekman MJ, von Schacky C
    "Human mononuclear cells express 12-LX: coordinated mRNA regulation with 5-LX and FLAP genes."
    Blood 87: 331-340 (1996)
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  • Breton J, Woolf D, Young P, Chabot-Fletcher M
    "Human keratinocytes lack the components to produce leukotriene B4."
    J Invest Dermatol 106: 162-167 (1996)
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  • De Carolis E, Denis D, Riendeau D
    "Oxidative inactivation of human 5-lipoxygenase in phosphatidylcholine vesicles."
    Eur J Biochem 235: 416-423 (1996)
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  • Hebert MJ, Takano T, Holthofer H, Brady HR
    "Sequential morphologic events during apoptosis of human neutrophils. Modulation by lipoxygenase-derived eicosanoids."
    J Immunol 157: 3105-3115 (1996)
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  • Ponton A, Thirion JP, Sirois P
    "Changes in chromatin conformation regulate the 5-lipoxygenase gene expression during differentiation of HL60 cells."
    Prostaglandins Leukot Essent Fatty Acids 55: 139-143 (1996)
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  • Bonnet C, Bertin P, Cook-Moreau J, Chable-Rabinovitch H, Treves R, Rigaud M
    "Lipoxygenase products and expression of 5-lipoxygenase and 5-lipoxygenase-activating protein in human cultured synovial cells."
    Prostaglandins 50: 127-135 (1995)
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  • Cortese JF, Spannhake EW, Eisinger W, Potter JJ, Yang VW
    "The 5-lipoxygenase pathway in cultured human intestinal epithelial cells."
    Prostaglandins 49: 155-166 (1995)
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  • Hutchinson JH, Charleson S, Evans JF, Falgueyret JP, Hoogsteen K, Jones TR, Kargman S, Macdonald D, McFarlane CS, Nicholson DW, et al.
    "Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase."
    J Med Chem 38: 4538-4547 (1995)
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  • Anderson KM, Seed T, Plate JM, Jajeh A, Meng J, Harris JE
    "Selective inhibitors of 5-lipoxygenase reduce CML blast cell proliferation and induce limited differentiation and apoptosis."
    Leuk Res 19: 789-801 (1995)
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  • Falgueyret JP, Denis D, Macdonald D, Hutchinson JH, Riendeau D
    "Characterization of the arachidonate and ATP binding sites of human 5-lipoxygenase using photoaffinity labeling and enzyme immobilization."
    Biochemistry 34: 13603-13611 (1995)
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  • Hammarberg T , Zhang YY , Lind B , Radmark O , Samuelsson B
    "Mutations at the C-terminal isoleucine and other potential iron ligands of 5-lipoxygenase."
    Eur J Biochem 230: 401-407 (1995)
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  • Janssen-Timmen U, Vickers PJ, Wittig U, Lehmann WD, Stark HJ, Fusenig NE, Rosenbach T, Radmark O, Samuelsson B, Habenicht AJ
    "Expression of 5-lipoxygenase in differentiating human skin keratinocytes."
    Proc Natl Acad Sci U S A 92: 6966-6970 (1995)
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  • Steinhilber D, Brungs M, Werz O, Wiesenberg I, Danielsson C, Kahlen JP, Nayeri S, Schrader M, Carlberg C
    "The nuclear receptor for melatonin represses 5-lipoxygenase gene expression in human B lymphocytes."
    J Biol Chem 270: 7037-7040 (1995)
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  • Woods JW, Coffey MJ, Brock TG, Singer II, Peters-Golden M
    "5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation."
    J Clin Invest 95: 2035-2046 (1995)
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  • Kuhn H., Belkner J., Suzuki H., Yamamoto S.
    "Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities."
    J. Lipid Res. 35: 1749-1759 (1994)
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  • Hatzelmann A, Fruchtmann R, Mohrs KH, Raddatz S, Matzke M, Pleiss U, Keldenich J, Muller-Peddinghaus R
    "Mode of action of the leukotriene synthesis (FLAP) inhibitor BAY X 1005: implications for biological regulation of 5-lipoxygenase."
    Agents Actions 43: 64-68 (1994)
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  • Hatzelmann A, Goossens J, Fruchtmann R, Mohrs KH, Raddatz S, Muller-Peddinghaus R
    "Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X1005 and other quinoline derivatives in intact cells and a cell-free system--implications for the function of 5-lipoxygenase activating protein."
    Biochem Pharmacol 47: 2259-2268 (1994)
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  • Janssen-Timmen U, Tomic I, Specht E, Beilecke U, Habenicht AJ
    "The arachidonic acid cascade, eicosanoids, and signal transduction."
    Ann N Y Acad Sci 733: 325-334 (1994)
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  • Lepley RA, Fitzpatrick FA
    "5-Lipoxygenase contains a functional Src homology 3-binding motif that interacts with the Src homology 3 domain of Grb2 and cytoskeletal proteins."
    J Biol Chem 269: 24163-24168 (1994)
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  • Muller K
    "5-Lipoxygenase and 12-lipoxygenase: attractive targets for the development of novel antipsoriatic drugs."
    Arch Pharm (Weinheim) 327: 3-19 (1994)
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  • Grimes D, Sturm RJ, Marinari LR, Carlson RP, Berkenkopf JW, Musser JH, Kreft AF, Weichman BM
    "WY-50,295 tromethamine, a novel, orally active 5-lipoxygenase inhibitor: biochemical characterization and antiallergic activity."
    Eur J Pharmacol 236: 217-228 (1993)
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  • Bell RL, Brooks DW, Young PR, Lanni C, Stewart AO, Bouska J, Malo PE, Carter GW
    "A-78773: a selective, potent 5-lipoxygenase inhibitor."
    J Lipid Mediat 6: 259-264 (1993)
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  • Bennett CF, Chiang MY, Monia BP, Crooke ST
    "Regulation of 5-lipoxygenase and 5-lipoxygenase-activating protein expression in HL-60 cells."
    Biochem J 289: 33-39 (1993)
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  • Ford-Hutchinson AW
    "5-Lipoxygenase activation in psoriasis: a dead issue?"
    Skin Pharmacol 6: 292-297 (1993)
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  • Piechele G, Colli S, Tremoli E, Maggi A
    "5-Lipoxygenase gene expression in HL60 cells during differentiation with DMSO."
    Pharmacol Res 27: 53-60 (1993)
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  • Ishii S., Noguchi M., Miyano M., Matsumoto T., Noma M.
    "Mutagenesis studies on the amino acid residues involved in the iron-binding and the activity of human 5-lipoxygenase."
    Biochem. Biophys. Res. Commun. 182: 1482-1490 (1992)
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  • Ethier D, Evans JF
    "Characterization of monoclonal antibodies against human leukocyte 5-lipoxygenase."
    Prostaglandins Leukot Essent Fatty Acids 45: 259-265 (1992)
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  • O'Leary VJ, Darley-Usmar VM, Russell LJ, Stone D
    "Pro-oxidant effects of lipoxygenase-derived peroxides on the copper-initiated oxidation of low-density lipoprotein."
    Biochem J 282: 631-634 (1992)
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  • Boado RJ , Pardridge WM , Vinters HV , Black KL
    "Differential expression of arachidonate 5-lipoxygenase transcripts in human brain tumors: evidence for the expression of a multitranscript family."
    Proc Natl Acad Sci U S A 89: 9044-9048 (1992)
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  • Evans JF, Leville C, Mancini JA, Prasit P, Therien M, Zamboni R, Gauthier JY, Fortin R, Charleson P, MacIntyre DE, et al.
    "5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors."
    Mol Pharmacol 40: 22-27 (1991)
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  • Funk CD, FitzGerald GA
    "Eicosanoid forming enzyme mRNA in human tissues. Analysis by quantitative polymerase chain reaction."
    J Biol Chem 266: 12508-12513 (1991)
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  • Samuelsson B , Hoshiko S , Radmark O
    "Characterization of the promoter of the human 5-lipoxygenase gene."
    Adv Prostaglandin Thromboxane Leukot Res 21: 1-8 (1991)
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  • Funk CD, Matsumoto T, Samuelsson B
    "Molecular biology and cloning of archidonate 5-lipoxygenase."
    Methods Enzymol 187: 491-501 (1990)
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  • Hoshiko S, Radmark O, Samuelsson B
    "Characterization of the human 5-lipoxygenase gene promoter."
    Proc Natl Acad Sci U S A 87: 9073-9077 (1990)
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  • Lewis RA, Austen KF, Soberman RJ
    "Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases."
    N Engl J Med 323: 645-655 (1990)
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  • Nakamura M, Matsumoto T, Noguchi M, Yamashita I, Noma M
    "Expression of a cDNA encoding human 5-lipoxygenase under control of the STA1 promoter in Saccharomyces cerevisiae."
    Gene 89: 231-237 (1990)
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  • Funk C.D., Hoshiko S., Matsumoto T., Raadmark O., Samuelsson B.
    "Characterization of the human 5-lipoxygenase gene."
    Proc. Natl. Acad. Sci. U.S.A. 86: 2587-2591 (1989)
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  • Funk CD, Gunne H, Steiner H, Izumi T, Samuelsson B
    "Native and mutant 5-lipoxygenase expression in a baculovirus/insect cell system."
    Proc Natl Acad Sci U S A 86: 2592-2596 (1989)
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  • Rouzer CA, Bennett CD, Diehl RE, Jones RE, Kargman S, Rands E, Dixon RA
    "Cloning and expression of human leukocyte 5-lipoxygenase."
    Adv Prostaglandin Thromboxane Leukot Res 19: 474-477 (1989)
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  • Matsumoto T., Funk C.D., Raadmark O., Hoeoeg J.-O., Joernvall H., Samuelsson B.
    "Molecular cloning and amino acid sequence of human 5-lipoxygenase."
    Proc. Natl. Acad. Sci. U.S.A. 85: 26-30 (1988)
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  • De Vries GW , Amdahl L , Mobasser A , Wenzel M , Wheeler LA
    "Preferential inhibition of 5-lipoxygenase activity by manoalide."
    Biochem Pharmacol 37: 2899-2905 (1988)
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  • Dixon RA, Jones RE, Diehl RE, Bennett CD, Kargman S, Rouzer CA
    "Cloning of the cDNA for human 5-lipoxygenase."
    Proc Natl Acad Sci U S A 85: 416-420 (1988)
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  • Guichardant M, Lagarde M
    "Monohydroxylated fatty acid substrate specificity of human leukocyte 5-lipoxygenase and omega-hydroxylase."
    Biochem J 256: 879-883 (1988)
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  • Jung G, Yang DC, Nakao A
    "Oxygenation of phosphatidylcholine by human polymorphonuclear leukocyte 15-lipoxygenase."
    Biochem Biophys Res Commun 130: 559-566 (1985)
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