Deutsches Krebsforschungszentrum 
German Cancer Resarch CenterLOX-DB - LipOXygenases DataBase
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LOX-DB - Literature related to flap-rat

Found 17 entries:

  • Escoubet-Lozach L , M'Rini C , Rey A , Beraud M , Lepert JC , Courtade M , Frisach MF , Pipy B
    "Increased expression of cytosolic phospholipase A2, 5-lipoxygenase and 5-lipoxygenase-activating protein in rat peritoneal macrophages during ovalbumin-induced sensitization."
    Clin Exp Allergy 31: 1094-1104 (2001)

  • Escoubet-Lozach L, M'Rini CF, Rey A, Beraud M, Lepert JC, Bernard J, Mathieu JR, Pipy B
    "Contrasting effect of interleukin-4 on the expression of cytosolic phospholipase A2, 5-lipoxygenase and 5-lipoxygenase-activating protein in peritoneal macrophages from control and ovalbumin-sensitized rats."
    Eur Cytokine Netw 12: 162-171 (2001)

  • Le Filliatre G, Sayah S, Latournerie V, Renaud JF, Finet M, Hanf R
    "Cyclo-oxygenase and lipoxygenase pathways in mast cell dependent-neurogenic inflammation induced by electrical stimulation of the rat saphenous nerve."
    Br J Pharmacol 132: 1581-1589 (2001)

  • Qu T, Uz T, Manev H
    "Inflammatory 5-LOX mRNA and protein are increased in brain of aging rats."
    Neurobiol Aging 21: 647-652 (2000)

  • Coffey MJ, Phare SM, Peters-Golden M
    "Prolonged exposure to lipopolysaccharide inhibits macrophage 5-lipoxygenase metabolism via induction of nitric oxide synthesis."
    J Immunol 165: 3592-3598 (2000)

  • Manev H, Uz T
    "Primary cultures of rat cerebellar granule cells as a model to study neuronal 5-lipoxygenase and FLAP gene expression."
    Ann N Y Acad Sci 890: 183-190 (1999)

  • Ozeki Y, Nagamura Y, Ito H, Unemi F, Kimura Y, Igawa T, Kambayashi J, Takahashi Y, Yoshimoto T
    "An anti-platelet agent, OPC-29030, inhibits translocation of 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid production in human platelets."
    Br J Pharmacol 128: 1699-1704 (1999)

  • Uz T, Dwivedi Y, Savani PD, Impagnatiello F, Pandey G, Manev H
    "Glucocorticoids stimulate inflammatory 5-lipoxygenase gene expression and protein translocation in the brain."
    J Neurochem 73: 693-699 (1999)

  • Phare SM , Peters-Golden M , Coffey MJ
    "Alveolar lining fluid regulates mononuclear phagocyte 5-lipoxygenase metabolism."
    Eur Respir J 12: 1141-1146 (1998)

  • Smirnov SV, Knock GA, Aaronson PI
    "Effects of the 5-lipoxygenase activating protein inhibitor MK886 on voltage-gated and Ca2+-activated K+ currents in rat arterial myocytes."
    Br J Pharmacol 124: 572-578 (1998)

  • Voelkel NF, Tuder RM, Wade K, Hoper M, Lepley RA, Goulet JL, Koller BH, Fitzpatrick F
    "Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats."
    J Clin Invest 97: 2491-2498 (1996)

  • Gyomber E, Vattay P, Szabo S, Rainsford KD
    "Effect of lipoxygenase inhibitors and leukotriene antagonists on acute and chronic gastric haemorrhagic mucosal lesions in ulcer models in the rat."
    J Gastroenterol Hepatol 11: 922-927 (1996)

  • Lammers CH, Schweitzer P, Facchinetti P, Arrang JM, Madamba SG, Siggins GR, Piomelli D
    "Arachidonate 5-lipoxygenase and its activating protein: prominent hippocampal expression and role in somatostatin signaling."
    J Neurochem 66: 147-152 (1996)

  • Vickers PJ, Adam M, Charleson S, Abramovitz M, O'Neill G, Mancini JA
    "Amino acid residues of 5-lipoxygenase-activating protein critical for the binding of leukotriene biosynthesis inhibitors."
    J Lipid Mediat 6: 31-42 (1993)

  • Vickers PJ, O'Neill GP, Mancini JA, Charleson S, Abramovitz M
    "Cross-species comparison of 5-lipoxygenase-activating protein."
    Mol Pharmacol 42: 1014-1019 (1992)

  • Dixon R.A., Diehl R.E., Opas E., Rands E., Vickers P.J., Evans J.F., Gillard J.W., Miller D.K.
    "Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis."
    Nature 343: 282-284 (1990)

  • Miller D.K., Gillard J.W., Vickers P.J., Sadowski S., Leveille C., Mancini J.A., Charleson P., Dixon R.A., Ford-Hutchinson A.W., Fortin R., et al.
    "Identification and isolation of a membrane protein necessary for leukotriene production."
    Nature 343: 278-281 (1990)