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Glycosciences.DB structure entry #6656: 6'-Sialyllactosamin
a-D-Neup5Ac-(2-6)-b-D-Galp-(1-4)-b-D-GlcpNAc
[][B-D-GLCPNAC]{[(4+1)][B-D-GALP]{[(6+2)][A-D-NEUP5AC]{}}}
RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
5s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(4+1)3d
3:3o(6+2)4d
4:4d(5+1)5n
<?xml version="1.0" encoding="UTF-8"?>
<sugar version="1.0">
<residues>
<basetype id="1" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dglc-HEX-1:5">
<stemtype id="1" type="dglc" />
</basetype>
<substituent id="2" name="n-acetyl" />
<basetype id="3" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dgal-HEX-1:5">
<stemtype id="1" type="dgal" />
</basetype>
<basetype id="4" anomer="a" superclass="non" ringStart="2" ringEnd="6" name="a-dgro-dgal-NON-2:6|1:a|2:keto|3:d">
<stemtype id="1" type="dgro" />
<stemtype id="2" type="dgal" />
<modification type="a" pos_one="1" />
<modification type="keto" pos_one="2" />
<modification type="d" pos_one="3" />
</basetype>
<substituent id="5" name="n-acetyl" />
</residues>
<linkages>
<connection id="1" parent="1" child="2">
<linkage id="1" parentType="d" childType="n">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
<connection id="2" parent="1" child="3">
<linkage id="2" parentType="o" childType="d">
<parent pos="4" />
<child pos="1" />
</linkage>
</connection>
<connection id="3" parent="3" child="4">
<linkage id="3" parentType="o" childType="d">
<parent pos="6" />
<child pos="2" />
</linkage>
</connection>
<connection id="4" parent="4" child="5">
<linkage id="4" parentType="d" childType="n">
<parent pos="5" />
<child pos="1" />
</linkage>
</connection>
</linkages>
</sugar>

1 - 5 of 10 entries with matching glycan part

a-D-Neup5Ac-(2-6)-b-D-Galp-(1-4)-b-D-GlcpNAc-(1-4)-Asn
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Taxons: 1 |

a-D-Neup5Ac-(2-6)-b-D-Galp-(1-4)-b-D-GlcpNAc-(1-1)-Methyl
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Taxons |

a-D-Neup5Ac-(2-6)-b-D-Galp-(1-4)-b-D-GlcpNAc-(1-4)+
|
Asn-(1-2)-Ser-(1-2)-Thr-(1-2)-Ile
|
<(allyloxy)carbonyl>-(1-2)-Phe-(1-2)+
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Taxons |

a-D-Neup5Ac-(2-6)-b-D-Galp-(1-4)-b-D-GlcpNAc-(1-4)+
|
Asn-(1-2)-Gly-(1-2)-Gly
|
Gly-(1-2)-Gly-(1-2)+
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Taxons |

a-D-Neup5Ac-(2-6)-b-D-Galp-(1-4)-b-D-GlcpNAc-(1-1)-Pent-4-en-1-ol
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Taxons |
- Lactosamine (Show) (Search Database)
- 6'-Sialyllactosamin
- 6SLN
- 6'-SLN
- 6'SLN
Chemical Formula: | C25H42N2O19 | #C | #H | #O | #N | |
Molec. Weight: | 674 | 25 | 42 | 19 | 2 | |
# Atoms: | 88 | |||||
# Residues: | 3 | |||||
# Heavy Atoms: | 46 |
Superclasses:
|
Residues:
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1 - 5 of 47 PDB entries

PDB ID 6y64:
Structure of Sheep Polyomavirus VP1 in complex with 6'-Sialyllactosamine
Description: Capsid protein VP1
Source: Sheep polyomavirus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6Å
Release date: 2020-07-08
Entry features 3 distinct glycan structures [6 instances].

PDB ID 6p4r:
Salmonella typhi PltB Homopentamer N29K Mutant with Neu5Ac-alpha-2-6-Gal-beta-1-4-GlcNAc glycans
Description: Putative pertussis-like toxin subunit
Source: Salmonella enterica subsp. enterica serovar Typhi str. CT18
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87Å
Release date: 2020-03-25
Entry features 1 distinct glycan structures [5 instances].

PDB ID 6p4n:
Salmonella typhi PltB Homopentamer with Neu5Ac-alpha-2-6-Gal-beta-1-4-GlcNAc Glycans
Description: Putative pertussis-like toxin subunit
Source: Salmonella enterica subsp. enterica serovar Typhi str. CT18
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7Å
Release date: 2020-03-25
Entry features 1 distinct glycan structures [3 instances].

PDB ID 6idb:
Crystal structure of H7 hemagglutinin mutant H7-SVTQ ( A138S, P221T, L226Q) with 6'SLN
Description: Hemagglutinin
Source: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.502Å
Release date: 2019-11-27
Entry features 2 distinct glycan structures [3 instances].

PDB ID 6tzb:
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin in complex with 6'-SLNLN
Description: Hemagglutinin HA1, Hemagglutinin HA2
Source: Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.243Å
Release date: 2019-10-30
Entry features 7 distinct glycan structures [16 instances].
1 - 5 of 17 literature references

Reference #22508
Munday RJ; Coradin T; Nimmo R; Lad Y; Hyde SC; Mitrophanos K; Gill DR
Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors.
Published 2022 in Mol Ther Methods Clin Dev, 26: 239-252
Reference contains 7 structures

Reference #21907
Enterina JR; Sarkar S; Streith L; Jung J; Arlian BM; Meyer SJ; Takematsu H; Xiao C; Baldwin TA; Nitschke L; Shlomchick MJ; Paulson JC; Macauley MS
Coordinated changes in glycosylation regulate the germinal center through CD22.
Published 2022 in Cell Rep, 38: 110512
Reference contains 2 structures

Reference #21602
Hyun JY; Kim S; Lee CH; Lee HS; Shin I
Efficient Preparation and Bioactivity Evaluation of Glycan-Defined Glycoproteins.
Published 2021 in ACS Chem Biol, 16: 1930-1940
Reference contains 9 structures

Reference #22000
Sojitra M; Sarkar S; Maghera J; Rodrigues E; Carpenter EJ; Seth S; Ferrer Vinals D; Bennett NJ; Reddy R; Khalil A; Xue X; Bell MR; Zheng RB; Zhang P; Nycholat C; Bailey JJ; Ling CC; Lowary TL; Paulson JC; Macauley MS; Derda R
Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage.
Published 2021 in Nat Chem Biol, 17: 806-816
Reference contains 65 structures

Reference #21752
Nguyen T; Lee S; Yang YA; Ahn C; Sim JH; Kei TG; Barnard KN; Yu H; Millano SK; Chen X; Parrish CR; Song J
The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication.
Published 2020 in PLoS Pathog, 16: e1008336
Reference contains 5 structures
1 - 5 of 21 literature references from PDB entries

Reference #22163
Lee S; Yang YA; Milano SK; Nguyen T; Ahn C; Sim JH; Thompson AJ; Hillpot EC; Yoo G; Paulson JC; Song J
Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence.
Published 2020 in Cell Host Microbe, 27: 937-949.e6

Reference #22238
Ströh LJ; Rustmeier NH; Blaum BS; Botsch J; Rößler P; Wedekink F; Lipkin WI; Mishra N; Stehle T
Structural Basis and Evolution of Glycan Receptor Specificities within the Polyomavirus Family.
Published 2020 in mBio, 11:

Reference #20218
Tzarum N; de Vries RP; Peng W; Thompson AJ; Bouwman KM; McBride R; Yu W; Zhu X; Verheije MH; Paulson JC; Wilson IA
The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Published 2017 in Cell Rep, 19: 235-245

Reference #20271
Wu NC; Xie J; Zheng T; Nycholat CM; Grande G; Paulson JC; Lerner RA; Wilson IA
Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Published 2017 in Cell Host Microbe, 21: 742-753.e8

Reference #20348
Ni F; Kondrashkina E; Wang Q
Determinant of receptor-preference switch in influenza hemagglutinin.
Published 2017 in Virology, 513: 98-107
NCBI Taxonomy ID | Scientific Name |
9606 | Homo sapiens |
Consortium for Functional Glycomics (CFG):
- carbNlink_42268_D000
- carbSynthe_0040_D000
- carbSynthe_0143_D000
- carbSynthe_0187_D000
- carbSynthe_0245_D000
- carbSynthe_0748_D000
- carbSynthe_0749_D000
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